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MRI-Topics

Workflow and Scan Protocol Considerations for Integrated Whole-Body PET/MRI in Oncology

By | MRI-Topics, Nuclear Medicine-topics | No Comments

Integrated PET/MRI systems open exciting possibilities for clinical and research applications. However, compared with PET/CT, PET/MRI is a complex technique resulting in new problems and challenges, especially regarding workflow, scan protocols, and data analysis. This complexity applies in particular to examinations in oncology with partial- or whole-body coverage extending over several bed positions. Unlike diagnostic PET/CT, for which the clinical CT protocols can largely be copied from stand-alone CT, the design of a diagnostic MRI
protocol for partial- or whole-body coverage is more complex and has to be adapted to the special requirements of PET/MRI to be both time-efficient and comprehensive. Here, we describe basic considerations concerning workflow, imaging protocols, and image analysis for whole-body PET/MRI in oncology, based on our experience with the first integrated PET/MRI
scanner.

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Intracranial Lesions with High Signal Intensity on T1-weighted MR Images: Differential Diagnosis

By | MRI-Topics | No Comments

Diverse categories of intracranial lesions appear bright at T1-weighted MR imaging. Familiarity with the types of substances and physical properties that contribute to T1 shortening is helpful for formulating an appropriate differential diagnosis and a systematic approach to the interpretation of high-signal-intensity lesions seen on T1-weighted images. Many disease entities have characteristic clinical and imaging features that allow definitive diagnosis.

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FLAIR2 : A Combination of FLAIR and T2 for Improved MS Lesion Detection 

By | MRI-Topics | No Comments

FLAIR and double inversion recovery are important MR imaging scans for MS. The suppression of signal
from CSF in FLAIR and the additional suppression of WM signal in double inversion recovery improve contrast between lesions, WM and
GM, albeit at a reduced SNR. However, whether the acquisition of double inversion recovery is necessary is still debated. Here, we present
an approach that allows obtaining CSF-suppressed images with improved contrast between lesions, WM and GM without strongly
penalizing SNR.

MRI image

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